Meet our Team

Dr. Karnis

Megan Freebury Karnis, B.A/Sc, MD, FRCSC

Medical Director

Dr. Karnis is originally from Toronto. She pursued her undergraduate studies at McMaster University, where she earned a Bachelor of Arts and Science degree. In 1993 she graduated from medical school at McMaster University. Dr. Karnis completed her internship at the University of Toronto, in the Department of Obstetrics and Gynecology and then returned to McMaster for her residency in Obstetrics and Gynecology. Upon completion of her residency, Dr. Karnis moved to Boston, Massachusetts where she engaged in a three year fellowship in Reproductive Endocrinology and Infertility at Harvard Medical School, in conjunction with the Beth Israel Deaconess Medical Center and Boston IVF. In 2002, Dr. Karnis returned to Canada. She is a fellow of the Royal College of Physicians and Surgeons of Canada and is U.S. Board Eligible in Obstetrics and Gynecology and Reproductive Endocrinology and Infertility. She is the REI program Director at McMaster University.

Her research interests are in the area of Turner syndrome and premature ovarian failure. She is internationally recognized as an expert in the risks of pregnancy in women with Turner syndrome. Her practice involves the management of patients with infertility, recurrent pregnancy loss, premature ovarian failure, polycystic ovarian syndrome and endocrinologic disorders affecting the female reproductive system. She also specializes in reproductive surgery including operative hysteroscopy and tubal reconstruction. Dr. Karnis doubles as a wife and mother of three young children.



Dr. Shilpa

Shilpa Amin, MD, FRCSC

Consultant, Fertility Specialist

Dr. Amin is a specialist in Reproductive Endocrinology and Infertility. She completed her medical training (1996), followed by a residency in Obstetrics and Gynecology, both at the University of Manitoba. On completion, she held a faculty position as lecturer at the University of Manitoba and practised general Obstetrics and Gynecology at St. Boniface General Hospital in Winnipeg. In 2002, she pursued a fellowship in Reproductive Medicine at the University of Ottawa.

Dr. Amin has published articles in the Society of Obstetrics and Gynecology Journal of Canada (SOGC), and The Journal of Pediatric and Adolescent Gynecology; and abstracts in Fertility and Sterility. She has also contributed to a poster session at an annual meeting of the American Society of Reproductive Medicine.

Her interests include all fields of Infertility and Reproductive Endocrinology including Polycystic Ovary Syndrome (PCOS) and Recurrent Pregnancy Loss (RPL) and endometriosis. She performs laparoscopic and hysteroscopic surgery for infertility, and has a special interest in Pediatric and Adolescent Gynecology. Dr. Amin is an Assistant Professor of Obstetrics and Gynecology at McMaster University and the acting supervisor for the residents in the McMaster University training program.

She doubles as a wife and mother of three, and is fluent in English and Hindi.



Mike Neal

Michael Neal, BSc. (Hons), MSc

Scientific Director

Michael Neal is one of the founding partners of ONE Fertility. He completed his Masters Degree in Biomedical Sciences at the University of Guelph, focusing on the reproductive consequences of chromosome abnormalities. His career in Human IVF started by working in a private clinic in Toronto, and he has since worked as a Laboratory Manager in public and private clinics since 2000.

Michael Neal’s experience in clinical Assisted Reproductive Technologies and his keen research interests have gained him an international reputation for innovation and excellence. He has numerous peer-reviewed publications and is a frequent reviewer for many major scientific journals related to reproduction. Mike is a recipient of the prestigious Laboratory Innovation in Fertility and Embryology (LIFE) Award. Recent honours include: Best Basic Science Paper, Best Clinical Paper, Alpha Exchange, and the R.T. Weaver Award, among other acknowledgements. In addition to his clinical responsibilities, Mike has research interests in the following areas: (a.) the effect of environmental contaminants on fertility, (b.) non-invasive measurements of embryo quality, and (c.) fertility preservation for male and female oncology patients.

Mike is a member of the Canadian Fertility and Andrology Society (CFAS); the American Society for Reproductive Medicine (ASRM); International Society for Fertility Preservation (ISFP); among others. He sits on the executive of the ART Lab SIG and is on the Board of Directors for CFAS. He is also on the Advisory Board of Fertile Future, a non-profit organization dedicated to helping cancer patients preserve their fertility.



Dr. Hughes

Edward G. Hughes, MBChB, MSc, FRCSC

Consultant, Fertility Specialist

Ed Hughes is a Professor Emeritus with the department of Obstetrics and Gynaecology at McMaster University. After receiving his medical degree from the University of Liverpool in England, Dr. Hughes obtained additional education in Leicester, England, and later at the University of Ottawa, Ontario. After residency, he completed four years of REI fellowship training, two at the University of Ottawa and a further two with IVF pioneers Alan Trounson and Carl Wood, in Monash University, Melbourne, Australia. Since joining the faculty at McMaster, Dr. Hughes has also completed a Masters Degree in clinical epidemiology and biostatistics.

In addition to training as an REI specialist, Dr. Hughes has worked as a GP in a remote area of Northern BC called Bella Bella, at a community hospital run by the United Church of Canada. He has many interests outside medicine, including fine art – check out his website at eghughes.ca for paintings, publications and workshops – cycling, windsurfing and skiing. Ed lives in Ancaster, Ontario with his wife (a pediatrician), their three children and many pets.

Dr. Hughes’ research interests include clinical epidemiology, effectiveness of sub-fertility treatments, the effects of smoking, aging and environmental exposures on reproduction, and the inhibin/TGFß peptide family. He led the only multi-centre randomized controlled trial of expectant management versus IVF (EMVI), as part of his strategy to encourage public funding for IVF. More recently, he has completed research work on Art Therapy as a healing tool for women dealing with infertility and has lectured on these and many other topics, both nationally and internationally.

Dr. Hughes is a fellow of the Royal College of Physicians and Surgeons of Canada. Author and coauthor of numerous publications, Dr. Hughes’ work has appeared in such journals as The Journal of Clinical Endocrinology and Metabolism, Human Reproduction, and Fertility and Sterility. He is a referee for The British Journal of Obstetrics and Gynaecology, Fertility and Sterility, Human Reproduction, and Canadian Medical Journal. He is an Associate Editor of the journal Human Reproduction and a founding editor of The Cochrane Collaboration Sub-Fertility module. Dr Hughes was a member of the Science Advisory Panel to the Agency for Human Reproduction Canada and is a past-president of the Canadian Fertility and Andrology Society, Canada’s premier organization representing all disciplines in the field of Fertility care.



Dr. Faghih

Mehrnoosh Faghih MD, FRCSC, FACOG

CONSULTANT, FERTILITY SPECIALIST

Dr. Mehrnoosh Faghih is a specialist in Reproductive Endocrinology and Infertility. She completed her two-year subspecialty fellowship in Gynecologic Reproductive Endocrinology and Infertility at McMaster University in 2010 and joined the practice at ONE Fertility. She completed a residency in Obstetrics and Gynecology at McMaster University in 2007, having obtained her Doctor of Medicine degree with honours at Isfahan Medical University, Iran in 2000.

Dr. Faghih is an Assistant Clinical Professor in the Department of Obstetrics and Gynecology at McMaster University and is an attending physician at Hamilton Health Sciences Hospitals. She is certified in both Obstetrics and Gynecology and Gynecologic Reproductive Endocrinology and Infertility by the Royal College of Physicians and Surgeons of Canada. She is also American board certified in Obstetrics and Gynecology, and is a fellow of the American Congress of Obstetricians and Gynecologists. She is a fellow of The Royal College of Physicians and Surgeons of Canada, and an active member of the Canadian Fertility and Andrology Society and the American Society for Reproductive Medicine.

Dr. Faghih’s practice includes all areas of reproductive care, with particular interest in female infertility, premature ovarian failure, polycystic ovary syndrome, endometriosis and recurrent pregnancy loss and minimally invasive gynecologic surgery. Dr. Faghih has advanced surgical skills in reproductive surgery and, during her residency, was awarded the AAGL certificate for Excellence in Endoscopic Procedures. She is also fluent in both English and Farsi.